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IPPS
2006
IEEE
15 years 3 months ago
An experimental study of optimizing bioinformatics applications
As bioinformatics is an emerging application of high performance computing, this paper first evaluates the memory performance of several representative bioinformatics application...
Guangming Tan, Lin Xu, Shengzhong Feng, Ninghui Su...
BIB
2008
86views more  BIB 2008»
14 years 10 months ago
Recent developments in the MAFFT multiple sequence alignment program
The accuracy and scalability of multiple sequence alignment (MSA) of DNAs and proteins have long been and are still important issues in bioinformatics. To rapidly construct a reas...
Kazutaka Katoh, Hiroyuki Toh
BMCBI
2008
134views more  BMCBI 2008»
14 years 10 months ago
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites
Background: Utilization of alternative initiation sites for protein translation directed by non-AUG codons in mammalian mRNAs is observed with increasing frequency. Alternative in...
Jill L. Wegrzyn, Thomas M. Drudge, Faramarz Valafa...
BMCBI
2008
162views more  BMCBI 2008»
14 years 10 months ago
Improved identification of conserved cassette exons using Bayesian networks
Background: Alternative splicing is a major contributor to the diversity of eukaryotic transcriptomes and proteomes. Currently, large scale detection of alternative splicing using...
Rileen Sinha, Michael Hiller, Rainer Pudimat, Ulri...
BMCBI
2007
114views more  BMCBI 2007»
14 years 10 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...