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CLEIEJ
2006
97views more  CLEIEJ 2006»
14 years 10 months ago
Prediction of RNA Pseudoknotted Secondary Structure using Stochastic Context Free Grammars (SCFG)
Pseudoknots are a frequent RNA structure that assumes essential roles for varied biocatalyst cell's functions. One of the most challenging fields in bioinformatics is the pre...
Rafael Garcia
BIOINFORMATICS
2006
130views more  BIOINFORMATICS 2006»
14 years 10 months ago
Memory efficient folding algorithms for circular RNA secondary structures
A small class of RNA molecules, in particular the tiny genomes of viroids, are circular. Yet most structure prediction algorithms handle only linear RNAs. The most straightforward ...
Ivo L. Hofacker, Peter F. Stadler
BMCBI
2008
116views more  BMCBI 2008»
14 years 10 months ago
A novel representation of RNA secondary structure based on element-contact graphs
Background: Depending on their specific structures, noncoding RNAs (ncRNAs) play important roles in many biological processes. Interest in developing new topological indices based...
Wenjie Shu, Xiaochen Bo, Zhiqiang Zheng, Shengqi W...
BIBM
2008
IEEE
105views Bioinformatics» more  BIBM 2008»
15 years 4 months ago
Energy Profile and Secondary Structure Impact shRNA Efficacy
Many characteristics of functional synthetic siRNAs have been identified. Our three-phase algorithm was developed to design siRNA on a wholegenome scale based on these characteris...
Hong Zhou, Xiao Zeng
ISSPIT
2010
14 years 4 months ago
Accelerating the Nussinov RNA folding algorithm with CUDA/GPU
Graphics processing units (GPU) on commodity video cards have evolved into powerful computational devices. The RNA secondary structure arises from the primary structure and a backb...
Dar-Jen Chang, Christopher Kimmer, Ming Ouyang