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BIBM
2007
IEEE
144views Bioinformatics» more  BIBM 2007»
14 years 18 days ago
Kinetic Modeling Using BioPAX Ontology
Thousands of biochemical interactions are available for download from curated databases such as Reactome, Pathway Interaction Database and other sources in the Biological Pathways...
Oliver Ruebenacker, Ion I. Moraru, James C. Schaff...
EVOW
2009
Springer
13 years 4 months ago
Evolutionary Approaches for Strain Optimization Using Dynamic Models under a Metabolic Engineering Perspective
One of the purposes of Systems Biology is the quantitative modeling of biochemical networks. In this effort, the use of dynamical mathematical models provides for powerful tools in...
Pedro Evangelista, Isabel Rocha, Eugénio C....
SAC
2008
ACM
13 years 5 months ago
Bayesian inference for a discretely observed stochastic kinetic model
The ability to infer parameters of gene regulatory networks is emerging as a key problem in systems biology. The biochemical data are intrinsically stochastic and tend to be observ...
Richard J. Boys, Darren J. Wilkinson, Thomas B. L....
BIOCOMP
2010
13 years 4 months ago
A Model Reduction Technique for Stochastic Biochemical Kinetics
Abstract-- Modeling the intermolecular reactions in a single cell is a critical problem in computational biology. Biochemical reaction systems often involve species in both low and...
Silvana Ilie, Ekaterina Kudashkina
BMCBI
2010
126views more  BMCBI 2010»
13 years 3 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...