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» Knowledge Extraction from Local Function Networks
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BMCBI
2008
100views more  BMCBI 2008»
14 years 10 months ago
High-precision high-coverage functional inference from integrated data sources
Background: Information obtained from diverse data sources can be combined in a principled manner using various machine learning methods to increase the reliability and range of k...
Bolan Linghu, Evan S. Snitkin, Dustin T. Holloway,...
CSB
2005
IEEE
180views Bioinformatics» more  CSB 2005»
15 years 4 months ago
Functional Modularity in a Large-Scale Mammalian Molecular Interaction Network
The Ingenuity™ Pathways Knowledge Base (IPKB) contains over one million findings manually curated from the scientific literature. Highly-structured content from the IPKB forms...
Andreas Kramer, Daniel R. Richards, James O. Bowlb...
WWW
2011
ACM
14 years 5 months ago
Towards semantic knowledge propagation from text corpus to web images
In this paper, we study the problem of transfer learning from text to images in the context of network data in which link based bridges are available to transfer the knowledge bet...
Guojun Qi, Charu C. Aggarwal, Thomas Huang
BMCBI
2008
103views more  BMCBI 2008»
14 years 10 months ago
Detection of protein catalytic residues at high precision using local network properties
Background: Identifying the active site of an enzyme is a crucial step in functional studies. While protein sequences and structures can be experimentally characterized, determini...
Patrick Slama, Ioannis Filippis, Michael Lappe
BMCBI
2010
136views more  BMCBI 2010»
14 years 10 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...