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95
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BMCBI
2008
95views more  BMCBI 2008»
15 years 17 days ago
Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
Alinda Nagy, Hédi Hegyi, Krisztina Farkas, ...
107
Voted
BMCBI
2006
166views more  BMCBI 2006»
15 years 15 days ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
201
Voted
BMCBI
2006
140views more  BMCBI 2006»
15 years 15 days ago
MACSIMS : multiple alignment of complete sequences information management system
Background: In the post-genomic era, systems-level studies are being performed that seek to explain complex biological systems by integrating diverse resources from fields such as...
Julie D. Thompson, Arnaud Muller, Andrew M. Waterh...
117
Voted
BMCBI
2007
105views more  BMCBI 2007»
15 years 14 days ago
Finding regulatory elements and regulatory motifs: a general probabilistic framework
Over the last two decades a large number of algorithms has been developed for regulatory motif finding. Here we show how many of these algorithms, especially those that model bind...
Erik van Nimwegen
BMCBI
2007
142views more  BMCBI 2007»
15 years 14 days ago
LinkHub: a Semantic Web system that facilitates cross-database queries and information retrieval in proteomics
nd: A key abstraction in representing proteomics knowledge is the notion of unique identifiers for individual entities (e.g. proteins) and the massive graph of relationships among...
Andrew K. Smith, Kei-Hoi Cheung, Kevin Y. Yip, Mar...