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115
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BMCBI
2008
106views more  BMCBI 2008»
15 years 4 months ago
Identification of hot-spot residues in protein-protein interactions by computational docking
Background: The study of protein-protein interactions is becoming increasingly important for biotechnological and therapeutic reasons. We can define two major areas therein: the s...
Solène Grosdidier, Juan Fernández-Re...
BMCBI
2008
184views more  BMCBI 2008»
15 years 4 months ago
Integrating protein-protein interactions and text mining for protein function prediction
Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
Samira Jaeger, Sylvain Gaudan, Ulf Leser, Dietrich...
142
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BMCBI
2006
166views more  BMCBI 2006»
15 years 4 months ago
Extraction of phylogenetic network modules from the metabolic network
Background: In bio-systems, genes, proteins and compounds are related to each other, thus forming complex networks. Although each organism has its individual network, some organis...
Takuji Yamada, Minoru Kanehisa, Susumu Goto
BMCBI
2006
143views more  BMCBI 2006»
15 years 3 months ago
Fast estimation of the difference between two PAM/JTT evolutionary distances in triplets of homologous sequences
Background: The estimation of the difference between two evolutionary distances within a triplet of homologs is a common operation that is used for example to determine which of t...
Christophe Dessimoz, Manuel Gil, Adrian Schneider,...
138
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DATAMINE
2006
130views more  DATAMINE 2006»
15 years 3 months ago
Mining Adaptive Ratio Rules from Distributed Data Sources
Different from traditional association-rule mining, a new paradigm called Ratio Rule (RR) was proposed recently. Ratio rules are aimed at capturing the quantitative association kno...
Jun Yan, Ning Liu, Qiang Yang, Benyu Zhang, QianSh...
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