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BMCBI
2010
191views more  BMCBI 2010»
14 years 12 months ago
BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
BMCBI
2006
143views more  BMCBI 2006»
14 years 12 months ago
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Background: Microarray technology produces gene expression data on a genomic scale for an endless variety of organisms and conditions. However, this vast amount of information nee...
Rainer König, Gunnar Schramm, Marcus Oswald, ...
BMCBI
2006
130views more  BMCBI 2006»
14 years 12 months ago
Docking protein domains in contact space
Background: Many biological processes involve the physical interaction between protein domains. Understanding these functional associations requires knowledge of the molecular str...
Stefano Lise, Alice Walker-Taylor, David T. Jones
ESWA
2007
127views more  ESWA 2007»
14 years 11 months ago
Clustering support vector machines for protein local structure prediction
Understanding the sequence-to-structure relationship is a central task in bioinformatics research. Adequate knowledge about this relationship can potentially improve accuracy for ...
Wei Zhong, Jieyue He, Robert W. Harrison, Phang C....
JCIT
2007
192views more  JCIT 2007»
14 years 11 months ago
Action Representation for Natural Language Interfaces to Agent Systems
In this paper, we outline a framework for the development of natural language interfaces to agent systems with a focus on action representation. The architecture comprises a natur...
Christel Kemke