23 search results - page 4 / 5 » Knowledge-based annotation of small molecule binding sites i... |
NAR
2011
14 years 10 days ago
2011
Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
NAR
2011
14 years 10 days ago
2011
A vast number of sweet tasting molecules are known, encompassing small compounds, carbohydrates, D-amino acids and large proteins. Carbohydrates play a particularly big role in hu...
BMCBI
2007
14 years 9 months ago
2007
Background: Computational prediction methods are currently used to identify genes in prokaryote genomes. However, identification of the correct translation initiation sites remain...
APBC
2003
14 years 11 months ago
2003
The interactions of large molecules with surfaces and with each other are strongly dependent upon their surface, rather than their bulk properties. In addition, the local properti...
BMCBI
2007
14 years 9 months ago
2007
Background: Ribozymes are small catalytic RNAs that possess the dual functions of sequencespecific RNA recognition and site-specific cleavage. Trans-cleaving ribozymes can inhibit...