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» Large scale hierarchical clustering of protein sequences
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BMCBI
2008
120views more  BMCBI 2008»
14 years 11 months ago
DBMLoc: a Database of proteins with multiple subcellular localizations
Background: Subcellular localization information is one of the key features to protein function research. Locating to a specific subcellular compartment is essential for a protein...
Song Zhang, Xuefeng Xia, Jincheng Shen, Yun Zhou, ...
SIGMOD
2001
ACM
200views Database» more  SIGMOD 2001»
15 years 11 months ago
Data Bubbles: Quality Preserving Performance Boosting for Hierarchical Clustering
In this paper, we investigate how to scale hierarchical clustering methods (such as OPTICS) to extremely large databases by utilizing data compression methods (such as BIRCH or ra...
Markus M. Breunig, Hans-Peter Kriegel, Peer Kr&oum...
BIBE
2005
IEEE
15 years 1 months ago
A Multi-Level Approach to SCOP Fold Recognition
The classification of proteins based on their structure can play an important role in the deduction or discovery of protein function. However, the relatively low number of solved...
Keith Marsolo, Srinivasan Parthasarathy, Chris H. ...
CIBCB
2005
IEEE
15 years 4 months ago
Toward Protein Structure Analysis with Self-Organizing Maps
- Establishing structure-function relationships on the proteomic scale is a unique challenge faced by bioinformatics and molecular biosciences. Large protein families represent nat...
Lutz Hamel, Gongqin Sun, Jing Zhang
CONSTRAINTS
2008
95views more  CONSTRAINTS 2008»
14 years 11 months ago
Efficient Sequence Alignment with Side-Constraints by Cluster Tree Elimination
Aligning DNA and protein sequences is a core technique in molecular biology. Often, it is desirable to include partial prior knowledge and conditions in an alignment. Going beyond...
Sebastian Will, Anke Busch, Rolf Backofen