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» Large scale hierarchical clustering of protein sequences
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BMCBI
2006
120views more  BMCBI 2006»
14 years 11 months ago
Integrating protein structures and precomputed genealogies in the Magnum database: Examples with cellular retinoid binding prote
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
Michael E. Bradley, Steven A. Benner
BMCBI
2011
14 years 2 months ago
Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
Holger Pillmann, Klas Hatje, Florian Odronitz, Bjo...
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BMCBI
2006
74views more  BMCBI 2006»
14 years 11 months ago
Protein protein interactions, evolutionary rate, abundance and age
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
Ramazan Saeed, Charlotte M. Deane
VIS
2007
IEEE
138views Visualization» more  VIS 2007»
16 years 11 days ago
Two Level Approach to Efficient Visualization of Protein Dynamics
Proteins are highly flexible and large amplitude deformations of their structure, also called slow dynamics, are often decisive to their function. We present a two-level rendering ...
Ove Daae Lampe, Ivan Viola, Nathalie Reuter, He...
BMCBI
2008
132views more  BMCBI 2008»
14 years 11 months ago
The SeqWord Genome Browser: an online tool for the identification and visualization of atypical regions of bacterial genomes thr
Background: Data mining in large DNA sequences is a major challenge in microbial genomics and bioinformatics. Oligonucleotide usage (OU) patterns provide a wealth of information f...
Hamilton Ganesan, Anna S. Rakitianskaia, Colin F. ...