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» Large scale hierarchical clustering of protein sequences
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JMLR
2010
175views more  JMLR 2010»
14 years 5 months ago
Hierarchical Convex NMF for Clustering Massive Data
We present an extension of convex-hull non-negative matrix factorization (CH-NMF) which was recently proposed as a large scale variant of convex non-negative matrix factorization ...
Kristian Kersting, Mirwaes Wahabzada, Christian Th...
BMCBI
2008
130views more  BMCBI 2008»
14 years 11 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
ISMB
1997
15 years 13 days ago
SEALS: A System for Easy Analysis of Lots of Sequences
We present a system of programs designed to facilitate sequence analysis projects involving large amounts of data. SEALS (System for Easy Analysis of Lots of Sequences) is a logic...
D. Roland Walker, Eugene V. Koonin
107
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BMCBI
2008
140views more  BMCBI 2008»
14 years 11 months ago
FUNYBASE: a FUNgal phYlogenomic dataBASE
Background: The increasing availability of fungal genome sequences provides large numbers of proteins for evolutionary and phylogenetic analyses. However the heterogeneity of data...
Sylvain Marthey, Gabriela Aguileta, Françoi...
BMCBI
2007
142views more  BMCBI 2007»
14 years 11 months ago
SABERTOOTH: protein structural alignment based on a vectorial structure representation
Background: The task of computing highly accurate structural alignments of proteins in very short computation time is still challenging. This is partly due to the complexity of pr...
Florian Teichert, Ugo Bastolla, Markus Porto