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» Large scale hierarchical clustering of protein sequences
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VISSOFT
2005
IEEE
15 years 4 months ago
Interactive Exploration of Semantic Clusters
Using visualization and exploration tools can be of great use for the understanding of a software system when only its source code is available. However, understanding a large sof...
Mircea Lungu, Adrian Kuhn, Tudor Gîrba, Mich...
112
Voted
BMCBI
2010
143views more  BMCBI 2010»
14 years 11 months ago
ETE: a python Environment for Tree Exploration
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
Jaime Huerta-Cepas, Joaquín Dopazo, Toni Ga...
CIKM
2005
Springer
15 years 4 months ago
Semantic similarity over the gene ontology: family correlation and selecting disjunctive ancestors
Many bioinformatics applications would benefit from comparing proteins based on their biological role rather than their sequence. In most biological databases, proteins are alrea...
Francisco M. Couto, Mário J. Silva, Pedro C...
112
Voted
BMCBI
2008
141views more  BMCBI 2008»
14 years 11 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...
BMCBI
2008
200views more  BMCBI 2008»
14 years 11 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia