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» Large scale hierarchical clustering of protein sequences
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BMCBI
2004
96views more  BMCBI 2004»
13 years 6 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2004
120views more  BMCBI 2004»
13 years 6 months ago
An approach to large scale identification of non-obvious structural similarities between proteins
Background: A new sequence independent bioinformatics approach allowing genome-wide search for proteins with similar three dimensional structures has been developed. By utilizing ...
Artem Cherkasov, Steven J. M. Jones
BIOINFORMATICS
2000
99views more  BIOINFORMATICS 2000»
13 years 6 months ago
GeneRAGE: a robust algorithm for sequence clustering and domain detection
Motivation: Efficient, accurate and automatic clustering of large protein sequence datasets, such as complete proteomes, into families, according to sequence similarity. Detection...
Anton J. Enright, Christos A. Ouzounis
BMCBI
2006
166views more  BMCBI 2006»
13 years 6 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...