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» Large-Scale Data Analysis Using Heuristic Methods
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108
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BMCBI
2008
92views more  BMCBI 2008»
15 years 2 months ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...
115
Voted
BMCBI
2010
173views more  BMCBI 2010»
15 years 2 months ago
The Yeast Resource Center Public Image Repository: A large database of fluorescence microscopy images
Background: There is increasing interest in the development of computational methods to analyze fluorescent microscopy images and enable automated large-scale analysis of the subc...
Michael Riffle, Trisha N. Davis
113
Voted
BMCBI
2010
117views more  BMCBI 2010»
15 years 2 months ago
MetAssimulo: Simulation of Realistic NMR Metabolic Profiles
Background: Probing the complex fusion of genetic and environmental interactions, metabolic profiling (or metabolomics/metabonomics), the study of small molecules involved in meta...
Harriet J. Muncey, Rebecca Jones, Maria De Iorio, ...
CGF
2008
142views more  CGF 2008»
15 years 2 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
CORR
2007
Springer
105views Education» more  CORR 2007»
15 years 2 months ago
Relative-Error CUR Matrix Decompositions
Many data analysis applications deal with large matrices and involve approximating the matrix using a small number of “components.” Typically, these components are linear combi...
Petros Drineas, Michael W. Mahoney, S. Muthukrishn...