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BMCBI
2007
128views more  BMCBI 2007»
14 years 9 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BMCBI
2007
109views more  BMCBI 2007»
14 years 9 months ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat
68
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ICDM
2008
IEEE
127views Data Mining» more  ICDM 2008»
15 years 4 months ago
The Impact of Structural Changes on Predictions of Diffusion in Networks
In a typical realistic scenario, there exist some past data about the structure of the network which are analyzed with respect to some possibly future spreading process, such as b...
Mayank Lahiri, Arun S. Maiya, Rajmonda Sulo, Habib...
BMCBI
2010
148views more  BMCBI 2010»
14 years 9 months ago
Analysis of interactions between ribosomal proteins and RNA structural motifs
Background: One important goal of structural bioinformatics is to recognize and predict the interactions between protein binding sites and RNA. Recently, a comprehensive analysis ...
Giovanni Ciriello, Claudio Gallina, Concettina Gue...
RECOMB
2009
Springer
15 years 10 months ago
COE: A General Approach for Efficient Genome-Wide Two-Locus Epistasis Test in Disease Association Study
The availability of high density single nucleotide polymorphisms (SNPs) data has made genome-wide association study computationally challenging. Twolocus epistasis (gene-gene inter...
Xiang Zhang, Feng Pan, Yuying Xie, Fei Zou, Wei Wa...