Sciweavers

303 search results - page 32 / 61
» Large-scale prediction of protein-protein interactions from ...
Sort
View
69
Voted
ICML
2008
IEEE
15 years 10 months ago
Detecting statistical interactions with additive groves of trees
Discovering additive structure is an important step towards understanding a complex multi-dimensional function because it allows the function to be expressed as the sum of lower-d...
Daria Sorokina, Rich Caruana, Mirek Riedewald, Dan...
RECOMB
2003
Springer
15 years 10 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
BIBM
2007
IEEE
104views Bioinformatics» more  BIBM 2007»
15 years 1 months ago
A Protocol to Detect Local Affinities Involved in Proteins Distant Interactions
The tridimensional structure of a protein is constrained or stabilized by some local interactions between distant residues of the protein, such as disulfide bonds, electrostatic i...
Christophe Nicolas Magnan, Cécile Capponi, ...
JCC
2008
99views more  JCC 2008»
14 years 8 months ago
Assessment of programs for ligand binding affinity prediction
: The prediction of the binding free energy between a ligand and a protein is an important component in the virtual screening and lead optimization of ligands for drug discovery. T...
Ryangguk Kim, Jeffrey Skolnick
BMCBI
2008
124views more  BMCBI 2008»
14 years 9 months ago
Inferring modules of functionally interacting proteins using the Bond Energy Algorithm
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
Ryosuke Watanabe, Enrique Morett, Edgar E. Vallejo