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110
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BMCBI
2006
152views more  BMCBI 2006»
15 years 13 days ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
BMCBI
2010
159views more  BMCBI 2010»
15 years 15 days ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
89
Voted
ISNN
2007
Springer
15 years 6 months ago
Online Dynamic Value System for Machine Learning
A novel online dynamic value system for machine learning is proposed in this paper. The proposed system has a dual network structure: data processing network (DPN) and information ...
Haibo He, Janusz A. Starzyk
86
Voted
ISBI
2009
IEEE
15 years 7 months ago
Probabilistic Branching Node Detection Using Hybrid Local Features
Probabilistic branching node inference is an important step for analyzing branching patterns involved in many anatomic structures. We propose combining machine learning techniques...
Haibin Ling, Michael Barnathan, Vasileios Megalooi...
110
Voted
BMCBI
2007
140views more  BMCBI 2007»
15 years 12 days ago
Accurate prediction of protein secondary structure and solvent accessibility by consensus combiners of sequence and structure in
Background: Structural properties of proteins such as secondary structure and solvent accessibility contribute to three-dimensional structure prediction, not only in the ab initio...
Gianluca Pollastri, Alberto J. M. Martin, Catherin...