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» Learning Methods for DNA Binding in Computational Biology
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JCB
2002
131views more  JCB 2002»
14 years 9 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
ISMB
2000
14 years 11 months ago
Pattern Recognition of Genomic Features with Microarrays: Site Typing of Mycobacterium Tuberculosis Strains
Mycobacterium tuberculosis (M. tb.) strains differ in the number and locations of a transposon-like insertion sequence known as IS6110. Accurate detection of this sequence can be ...
Soumya Raychaudhuri, Joshua M. Stuart, Xuemin Liu,...
BMCBI
2010
154views more  BMCBI 2010»
14 years 9 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
BMCBI
2008
143views more  BMCBI 2008»
14 years 9 months ago
Automatic detection of exonic splicing enhancers (ESEs) using SVMs
Background: Exonic splicing enhancers (ESEs) activate nearby splice sites and promote the inclusion (vs. exclusion) of exons in which they reside, while being a binding site for S...
Britta Mersch, Alexander Gepperth, Sándor S...
BMCBI
2008
123views more  BMCBI 2008»
14 years 9 months ago
Pol II promoter prediction using characteristic 4-mer motifs: a machine learning approach
Background: Eukaryotic promoter prediction using computational analysis techniques is one of the most difficult jobs in computational genomics that is essential for constructing a...
Firoz Anwar, Syed Murtuza Baker, Taskeed Jabid, Md...