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BMCBI
2006
152views more  BMCBI 2006»
14 years 9 months ago
A two-stage approach for improved prediction of residue contact maps
Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...
Alessandro Vullo, Ian Walsh, Gianluca Pollastri
BMCBI
2006
159views more  BMCBI 2006»
14 years 9 months ago
EVEREST: automatic identification and classification of protein domains in all protein sequences
Background: Proteins are comprised of one or several building blocks, known as domains. Such domains can be classified into families according to their evolutionary origin. Wherea...
Elon Portugaly, Amir Harel, Nathan Linial, Michal ...
79
Voted
BMCBI
2006
100views more  BMCBI 2006»
14 years 9 months ago
Using the nucleotide substitution rate matrix to detect horizontal gene transfer
Background: Horizontal gene transfer (HGT) has allowed bacteria to evolve many new capabilities. Because transferred genes perform many medically important functions, such as conf...
Micah Hamady, M. D. Betterton, Rob Knight
BMCBI
2006
112views more  BMCBI 2006»
14 years 9 months ago
Protein disorder prediction by condensed PSSM considering propensity for order or disorder
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
Chung-Tsai Su, Chien-Yu Chen, Yu-Yen Ou
75
Voted
COR
2006
97views more  COR 2006»
14 years 9 months ago
Evaluating the performance of cost-based discretization versus entropy- and error-based discretization
Discretization is defined as the process that divides continuous numeric values into intervals of discrete categorical values. In this article, the concept of cost-based discretiz...
Davy Janssens, Tom Brijs, Koen Vanhoof, Geert Wets