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JCB
2007
130views more  JCB 2007»
14 years 9 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
ICONIP
2010
14 years 6 months ago
Exploring Features and Classifiers to Classify MicroRNA Expression Profiles of Human Cancer
Recently, some non-coding small RNAs, known as microRNAs (miRNA), have drawn a lot of attention to identify their role in gene regulation and various biological processes. The miRN...
Kyung-Joong Kim, Sung-Bae Cho
BMCBI
2008
169views more  BMCBI 2008»
14 years 9 months ago
A comprehensive comparison of random forests and support vector machines for microarray-based cancer classification
Background: Cancer diagnosis and clinical outcome prediction are among the most important emerging applications of gene expression microarray technology with several molecular sig...
Alexander R. Statnikov, Lily Wang, Constantin F. A...
BMCBI
2010
116views more  BMCBI 2010»
14 years 9 months ago
FiGS: a filter-based gene selection workbench for microarray data
Background: The selection of genes that discriminate disease classes from microarray data is widely used for the identification of diagnostic biomarkers. Although various gene sel...
Taeho Hwang, Choong-Hyun Sun, Taegyun Yun, Gwan-Su...
BMCBI
2007
207views more  BMCBI 2007»
14 years 9 months ago
Discovering biomarkers from gene expression data for predicting cancer subgroups using neural networks and relational fuzzy clus
Background: The four heterogeneous childhood cancers, neuroblastoma, non-Hodgkin lymphoma, rhabdomyosarcoma, and Ewing sarcoma present a similar histology of small round blue cell...
Nikhil R. Pal, Kripamoy Aguan, Animesh Sharma, Shu...