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BMCBI
2006
159views more  BMCBI 2006»
15 years 5 months ago
Prediction of protein continuum secondary structure with probabilistic models based on NMR solved structures
Background: The structure of proteins may change as a result of the inherent flexibility of some protein regions. We develop and explore probabilistic machine learning methods for...
Mikael Bodén, Zheng Yuan, Timothy L. Bailey
BMCBI
2006
127views more  BMCBI 2006»
15 years 5 months ago
Automatic discovery of cross-family sequence features associated with protein function
Background: Methods for predicting protein function directly from amino acid sequences are useful tools in the study of uncharacterised protein families and in comparative genomic...
Markus Brameier, Josien Haan, Andrea Krings, Rober...
BMCBI
2006
152views more  BMCBI 2006»
15 years 5 months ago
A two-stage approach for improved prediction of residue contact maps
Background: Protein topology representations such as residue contact maps are an important intermediate step towards ab initio prediction of protein structure. Although improvemen...
Alessandro Vullo, Ian Walsh, Gianluca Pollastri
BMCBI
2006
105views more  BMCBI 2006»
15 years 5 months ago
CRNPRED: highly accurate prediction of one-dimensional protein structures by large-scale critical random networks
Background: One-dimensional protein structures such as secondary structures or contact numbers are useful for three-dimensional structure prediction and helpful for intuitive unde...
Akira R. Kinjo, Ken Nishikawa
BMCBI
2006
154views more  BMCBI 2006»
15 years 5 months ago
Automated recognition of malignancy mentions in biomedical literature
Background: The rapid proliferation of biomedical text makes it increasingly difficult for researchers to identify, synthesize, and utilize developed knowledge in their fields of ...
Yang Jin, Ryan T. McDonald, Kevin Lerman, Mark A. ...
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