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» Learning from Highly Structured Data by Decomposition
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BMCBI
2007
126views more  BMCBI 2007»
14 years 10 months ago
High-throughput identification of interacting protein-protein binding sites
Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Jo-Lan Chung, Wei Wang, Philip E. Bourne
BMCBI
2010
117views more  BMCBI 2010»
14 years 10 months ago
MetAssimulo: Simulation of Realistic NMR Metabolic Profiles
Background: Probing the complex fusion of genetic and environmental interactions, metabolic profiling (or metabolomics/metabonomics), the study of small molecules involved in meta...
Harriet J. Muncey, Rebecca Jones, Maria De Iorio, ...
BMCBI
2010
134views more  BMCBI 2010»
14 years 10 months ago
R-Gada: a fast and flexible pipeline for copy number analysis in association studies
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
Roger Pique-Regi, Alejandro Cáceres, Juan R...
KDD
2008
ACM
264views Data Mining» more  KDD 2008»
15 years 10 months ago
Stable feature selection via dense feature groups
Many feature selection algorithms have been proposed in the past focusing on improving classification accuracy. In this work, we point out the importance of stable feature selecti...
Lei Yu, Chris H. Q. Ding, Steven Loscalzo
BMCBI
2007
116views more  BMCBI 2007»
14 years 9 months ago
MED: a new non-supervised gene prediction algorithm for bacterial and archaeal genomes
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
Huaiqiu Zhu, Gang-Qing Hu, Yi-Fan Yang, Jin Wang, ...