Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
One of the most widely used techniques for data clustering is agglomerative clustering. Such algorithms have been long used across many different fields ranging from computational...
Our goal is to fit the multiple instances (or structures) of a generic model existing in data. Here we propose a novel model selection scheme to estimate the number of genuine str...
Machine learning methods that can use additional knowledge in their inference process are central to the development of integrative bioinformatics. Inclusion of background knowled...
Minca Mramor, Marko Toplak, Gregor Leban, Tomaz Cu...
Abstract. In this study we propose a novel model for the representation of biological networks and provide algorithms for learning model parameters from experimental data. Our appr...