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148
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BMCBI
2010
15 years 4 months ago
2010
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
171
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BMCBI
2007
15 years 4 months ago
2007
Background: Motif discovery aims to detect short, highly conserved patterns in a collection of unaligned DNA or protein sequences. Discriminative motif finding algorithms aim to i...
166
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BMCBI
2008
15 years 4 months ago
2008
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
158
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BMCBI
2006
15 years 4 months ago
2006
Background: Many vital biological processes, including transcription and splicing, require a combination of short, degenerate sequence patterns, or motifs, adjacent to defined seq...
143
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BMCBI
2006
2006
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
15 years 4 months ago
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...