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GPEM
2008
98views more  GPEM 2008»
14 years 11 months ago
Sporadic model building for efficiency enhancement of the hierarchical BOA
Efficiency enhancement techniques--such as parallelization and hybridization--are among the most important ingredients of practical applications of genetic and evolutionary algori...
Martin Pelikan, Kumara Sastry, David E. Goldberg
BMCBI
2006
137views more  BMCBI 2006»
14 years 11 months ago
Sigma: multiple alignment of weakly-conserved non-coding DNA sequence
Background: Existing tools for multiple-sequence alignment focus on aligning protein sequence or protein-coding DNA sequence, and are often based on extensions to Needleman-Wunsch...
Rahul Siddharthan
BMCBI
2006
139views more  BMCBI 2006»
14 years 11 months ago
DNA Molecule Classification Using Feature Primitives
Background: We present a novel strategy for classification of DNA molecules using measurements from an alpha-Hemolysin channel detector. The proposed approach provides excellent c...
Raja Tanveer Iqbal, Matthew Landry, Stephen Winter...
BMCBI
2006
202views more  BMCBI 2006»
14 years 11 months ago
Integrated biclustering of heterogeneous genome-wide datasets for the inference of global regulatory networks
Background: The learning of global genetic regulatory networks from expression data is a severely under-constrained problem that is aided by reducing the dimensionality of the sea...
David J. Reiss, Nitin S. Baliga, Richard Bonneau
COR
2006
97views more  COR 2006»
14 years 11 months ago
Evaluating the performance of cost-based discretization versus entropy- and error-based discretization
Discretization is defined as the process that divides continuous numeric values into intervals of discrete categorical values. In this article, the concept of cost-based discretiz...
Davy Janssens, Tom Brijs, Koen Vanhoof, Geert Wets