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» Learning with Globally Predictive Tests
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BMCBI
2008
138views more  BMCBI 2008»
14 years 9 months ago
Using neural networks and evolutionary information in decoy discrimination for protein tertiary structure prediction
Background: We present a novel method of protein fold decoy discrimination using machine learning, more specifically using neural networks. Here, decoy discrimination is represent...
Ching-Wai Tan, David T. Jones
MICCAI
2009
Springer
15 years 11 months ago
Predictive Simulation of Bidirectional Glenn Shunt Using a Hybrid Blood Vessel Model
Abstract. This paper proposes a method for performing predictive simulation of cardiac surgery. It applies a hybrid approach to model the deformation of blood vessels. The hybrid b...
Hao Li, Wee Kheng Leow, Ing-Sh Chiu
97
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BMCBI
2006
174views more  BMCBI 2006»
14 years 9 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
BMCBI
2006
134views more  BMCBI 2006»
14 years 9 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
JCB
2006
185views more  JCB 2006»
14 years 9 months ago
A Probabilistic Methodology for Integrating Knowledge and Experiments on Biological Networks
Biological systems are traditionally studied by focusing on a specific subsystem, building an intuitive model for it, and refining the model using results from carefully designed ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...