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IJDMB
2007
110views more  IJDMB 2007»
14 years 9 months ago
Transductive learning with EM algorithm to classify proteins based on phylogenetic profiles
: Phylogenetic profiles of proteins  strings of ones and zeros encoding respectively the presence and absence of proteins in a group of genomes  have recently been used to id...
Roger A. Craig, Li Liao
METMBS
2003
255views Mathematics» more  METMBS 2003»
14 years 11 months ago
Causal Explorer: A Causal Probabilistic Network Learning Toolkit for Biomedical Discovery
Causal Probabilistic Networks (CPNs), (a.k.a. Bayesian Networks, or Belief Networks) are well-established representations in biomedical applications such as decision support system...
Constantin F. Aliferis, Ioannis Tsamardinos, Alexa...
BMCBI
2010
159views more  BMCBI 2010»
14 years 10 months ago
Predicting domain-domain interaction based on domain profiles with feature selection and support vector machines
Background: Protein-protein interaction (PPI) plays essential roles in cellular functions. The cost, time and other limitations associated with the current experimental methods ha...
Alvaro J. González, Li Liao
BMCBI
2010
102views more  BMCBI 2010»
14 years 10 months ago
Peptide binding predictions for HLA DR, DP and DQ molecules
Background: MHC class II binding predictions are widely used to identify epitope candidates in infectious agents, allergens, cancer and autoantigens. The vast majority of predicti...
Peng Wang, John Sidney, Yohan Kim, Alessandro Sett...
BMCBI
2006
150views more  BMCBI 2006»
14 years 9 months ago
Predicting protein subcellular locations using hierarchical ensemble of Bayesian classifiers based on Markov chains
Background: The subcellular location of a protein is closely related to its function. It would be worthwhile to develop a method to predict the subcellular location for a given pr...
Alla Bulashevska, Roland Eils