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BMCBI
2010
130views more  BMCBI 2010»
15 years 3 months ago
Amino acid "little Big Bang": Representing amino acid substitution matrices as dot products of Euclidian vectors
Background: Sequence comparisons make use of a one-letter representation for amino acids, the necessary quantitative information being supplied by the substitution matrices. This ...
Karel Zimmermann, Jean-François Gibrat
FUIN
2011
358views Cryptology» more  FUIN 2011»
14 years 6 months ago
Unsupervised and Supervised Learning Approaches Together for Microarray Analysis
In this article, a novel concept is introduced by using both unsupervised and supervised learning. For unsupervised learning, the problem of fuzzy clustering in microarray data as ...
Indrajit Saha, Ujjwal Maulik, Sanghamitra Bandyopa...
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ESANN
2004
15 years 4 months ago
Sparse LS-SVMs using additive regularization with a penalized validation criterion
This paper is based on a new way for determining the regularization trade-off in least squares support vector machines (LS-SVMs) via a mechanism of additive regularization which ha...
Kristiaan Pelckmans, Johan A. K. Suykens, Bart De ...
NIPS
2004
15 years 4 months ago
Density Level Detection is Classification
We show that anomaly detection can be interpreted as a binary classification problem. Using this interpretation we propose a support vector machine (SVM) for anomaly detection. We...
Ingo Steinwart, Don R. Hush, Clint Scovel
BMCBI
2011
14 years 6 months ago
Learning sparse models for a dynamic Bayesian network classifier of protein secondary structure
Background: Protein secondary structure prediction provides insight into protein function and is a valuable preliminary step for predicting the 3D structure of a protein. Dynamic ...
Zafer Aydin, Ajit Singh, Jeff Bilmes, William Staf...