Background: With the advent of increasing sequence and structural data, a number of methods have been proposed to locate putative protein binding sites from protein surfaces. Ther...
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Background: Prediction of disulfide bridges from protein sequences is useful for characterizing structural and functional properties of proteins. Several methods based on differen...
Marc Vincent, Andrea Passerini, Matthieu Labb&eacu...
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Neil D. Lawrence, Magnus Rattra...