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BMCBI
2010
172views more  BMCBI 2010»
15 years 1 months ago
Accessing the SEED genome databases via Web services API: tools for programmers
Background: The SEED integrates many publicly available genome sequences into a single resource. The database contains accurate and up-to-date annotations based on the subsystems ...
Terry Disz, Sajia Akhter, Daniel Cuevas, Robert Ol...
BMCBI
2007
146views more  BMCBI 2007»
15 years 1 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2008
84views more  BMCBI 2008»
15 years 1 months ago
poolHiTS: A Shifted Transversal Design based pooling strategy for high-throughput drug screening
Background: A key goal of drug discovery is to increase the throughput of small molecule screens without sacrificing screening accuracy. High-throughput screening (HTS) in drug di...
Raghunandan M. Kainkaryam, Peter J. Woolf
BMCBI
2008
101views more  BMCBI 2008»
15 years 1 months ago
Scipio: Using protein sequences to determine the precise exon/intron structures of genes and their orthologs in closely related
Background: For many types of analyses, data about gene structure and locations of non-coding regions of genes are required. Although a vast amount of genomic sequence data is ava...
Oliver Keller, Florian Odronitz, Mario Stanke, Mar...
CACM
2008
131views more  CACM 2008»
15 years 1 months ago
Exterminator: Automatically correcting memory errors with high probability
Programs written in C and C++ are susceptible to memory errors, including buffer overflows and dangling pointers. These errors, which can lead to crashes, erroneous execution, and...
Gene Novark, Emery D. Berger, Benjamin G. Zorn