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BMCBI
2007
157views more  BMCBI 2007»
14 years 10 months ago
Impact of image segmentation on high-content screening data quality for SK-BR-3 cells
Background: High content screening (HCS) is a powerful method for the exploration of cellular signalling and morphology that is rapidly being adopted in cancer research. HCS uses ...
Andrew A. Hill, Peter LaPan, Yizheng Li, Steve Han...
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BMCBI
2007
138views more  BMCBI 2007»
14 years 10 months ago
A full Bayesian hierarchical mixture model for the variance of gene differential expression
Background: In many laboratory-based high throughput microarray experiments, there are very few replicates of gene expression levels. Thus, estimates of gene variances are inaccur...
Samuel O. M. Manda, Rebecca E. Walls, Mark S. Gilt...
BMCBI
2008
167views more  BMCBI 2008»
14 years 10 months ago
Expression profiles of switch-like genes accurately classify tissue and infectious disease phenotypes in model-based classificat
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
Michael Gormley, Aydin Tozeren
BMCBI
2008
160views more  BMCBI 2008»
14 years 10 months ago
A comparison of four clustering methods for brain expression microarray data
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...
CORR
2010
Springer
146views Education» more  CORR 2010»
14 years 10 months ago
Active Learning for Hidden Attributes in Networks
In many networks, vertices have hidden attributes that are correlated with the network's topology. For instance, in social networks, people are more likely to be friends if t...
Xiaoran Yan, Yaojia Zhu, Jean-Baptiste Rouquier, C...