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BMCBI
2010
109views more  BMCBI 2010»
15 years 2 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
BMCBI
2008
120views more  BMCBI 2008»
15 years 2 months ago
E-CAI: a novel server to estimate an expected value of Codon Adaptation Index (eCAI)
Background: The Codon Adaptation Index (CAI) is a measure of the synonymous codon usage bias for a DNA or RNA sequence. It quantifies the similarity between the synonymous codon u...
Pere Puigbò, Ignacio G. Bravo, Santiago Gar...
BMCBI
2006
179views more  BMCBI 2006»
15 years 2 months ago
Multiscale Hy3S: Hybrid stochastic simulation for supercomputers
Background: Stochastic simulation has become a useful tool to both study natural biological systems and design new synthetic ones. By capturing the intrinsic molecular fluctuation...
Howard Salis, Vassilios Sotiropoulos, Yiannis N. K...
BMCBI
2006
159views more  BMCBI 2006»
15 years 2 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
92
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COR
2006
129views more  COR 2006»
15 years 2 months ago
Game-theoretic analysis of an ancient Chinese horse race problem
This paper analyzes a legendary Chinese horse race problem involving the King of Qi and General Tianji which took place more than 2000 years ago. In this problem each player owns ...
Mingming Leng, Mahmut Parlar