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BMCBI
2008
111views more  BMCBI 2008»
14 years 11 months ago
SimHap GUI: An intuitive graphical user interface for genetic association analysis
Background: Researchers wishing to conduct genetic association analysis involving single nucleotide polymorphisms (SNPs) or haplotypes are often confronted with the lack of user-f...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
BMCBI
2008
135views more  BMCBI 2008»
14 years 11 months ago
Fregene: Simulation of realistic sequence-level data in populations and ascertained samples
Background: FREGENE simulates sequence-level data over large genomic regions in large populations. Because, unlike coalescent simulators, it works forwards through time, it allows...
Marc Chadeau-Hyam, Clive J. Hoggart, Paul F. O'Rei...
BMCBI
2006
85views more  BMCBI 2006»
14 years 11 months ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
JUCS
2008
210views more  JUCS 2008»
14 years 11 months ago
Systematic Characterisation of Objects in Digital Preservation: The eXtensible Characterisation Languages
: During the last decades, digital objects have become the primary medium to create, shape, and exchange information. However, in contrast to analog objects such as books that dire...
Christoph Becker, Andreas Rauber, Volker Heydegger...
BMCBI
2005
91views more  BMCBI 2005»
14 years 11 months ago
Providing visualisation support for the analysis of anatomy ontology data
Background: Improvements in technology have been accompanied by the generation of large amounts of complex data. This same technology must be harnessed effectively if the knowledg...
Aba-Sah Dadzie, Albert Burger