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148
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HASKELL
2008
ACM
15 years 6 months ago
2008
ACM
The quality of a programming language itself is only one component in the ability of application writers to get the job done. Programming languages can succeed or fail based on th...
118
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BMCBI
2010
15 years 5 months ago
2010
Background: Bisulfite sequencing using next generation sequencers yields genome-wide measurements of DNA methylation at single nucleotide resolution. Traditional aligners are not ...
127
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BMCBI
2010
15 years 5 months ago
2010
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
142
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BMCBI
2007
15 years 5 months ago
2007
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
152
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BMCBI
2007
15 years 5 months ago
2007
Background: Serial analysis of gene expression (SAGE) is used to obtain quantitative snapshots of the transcriptome. These profiles are count-based and are assumed to follow a Bin...