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BMCBI
2008
15 years 1 months ago
2008
Background: High-throughput screening of pharmaceutical compound activity in tissue culture experiments requires time-consuming repeated analysis of the large amounts of data gene...
131
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BMCBI
2010
15 years 1 months ago
2010
Background: Data generated using `omics' technologies are characterized by high dimensionality, where the number of features measured per subject vastly exceeds the number of...
125
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BMCBI
2007
15 years 1 months ago
2007
Background: Sequence motifs representing transcription factor binding sites (TFBS) are commonly encoded as position frequency matrices (PFM) or degenerate consensus sequences (CS)...
116
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BMCBI
2008
15 years 1 months ago
2008
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
102
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BMCBI
2008
15 years 1 months ago
2008
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...