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BMCBI
2006
145views more  BMCBI 2006»
15 years 1 months ago
Querying the public databases for sequences using complex keywords contained in the feature lines
Background: High throughput technologies often require the retrieval of large data sets of sequences. Retrieval of EMBL or GenBank entries using keywords is easy using tools such ...
Olivier Croce, Michaël Lamarre, Richard Chris...
BMCBI
2006
101views more  BMCBI 2006»
15 years 1 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
BMCBI
2006
87views more  BMCBI 2006»
15 years 1 months ago
Prediction of indirect interactions in proteins
Background: Both direct and indirect interactions determine molecular recognition of ligands by proteins. Indirect interactions can be defined as effects on recognition controlled...
Peteris Prusis, Staffan Uhlén, Ramona Petro...
BMCBI
2006
216views more  BMCBI 2006»
15 years 1 months ago
Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
BMCBI
2006
158views more  BMCBI 2006»
15 years 1 months ago
Parallelization of multicategory support vector machines (PMC-SVM) for classifying microarray data
Background: Multicategory Support Vector Machines (MC-SVM) are powerful classification systems with excellent performance in a variety of data classification problems. Since the p...
Chaoyang Zhang, Peng Li, Arun Rajendran, Youping D...