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BMCBI
2010
124views more  BMCBI 2010»
15 years 2 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
CORR
2010
Springer
117views Education» more  CORR 2010»
15 years 2 months ago
Evolution with Drifting Targets
We consider the question of the stability of evolutionary algorithms to gradual changes, or drift, in the target concept. We define an algorithm to be resistant to drift if, for s...
Varun Kanade, Leslie G. Valiant, Jennifer Wortman ...
BMCBI
2006
97views more  BMCBI 2006»
15 years 1 months ago
Goulphar: rapid access and expertise for standard two-color microarray normalization methods
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
Sophie Lemoine, Florence Combes, Nicolas Servant, ...
JCB
2008
106views more  JCB 2008»
15 years 1 months ago
Statistics of Random Protein Superpositions: p-Values for Pairwise Structure Alignment
Quantification of statistical significance is essential for the interpretation of protein structural similarity. To address this, a random model for protein structure comparison w...
James O. Wrabl, Nick V. Grishin
CORR
2007
Springer
91views Education» more  CORR 2007»
15 years 1 months ago
Unequal dimensional small balls and quantization on Grassmann Manifolds
—The Grassmann manifold Gn,p (L) is the set of all p-dimensional planes (through the origin) in the n-dimensional Euclidean space Ln , where L is either R or C. This paper consid...
Wei Dai, Brian Rider, Youjian Liu