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BMCBI
2010
144views more  BMCBI 2010»
14 years 11 months ago
Finding sRNA generative locales from high-throughput sequencing data with NiBLS
Background: Next-generation sequencing technologies allow researchers to obtain millions of sequence reads in a single experiment. One important use of the technology is the seque...
Daniel MacLean, Vincent Moulton, David J. Studholm...
BMCBI
2007
132views more  BMCBI 2007»
14 years 11 months ago
TPRpred: a tool for prediction of TPR-, PPR- and SEL1-like repeats from protein sequences
Background: Solenoid repeat proteins of the Tetratrico Peptide Repeat (TPR) family are involved as scaffolds in a broad range of protein-protein interactions. Several resources ar...
Manjunatha R. Karpenahalli, Andrei N. Lupas, Johan...
BMCBI
2007
106views more  BMCBI 2007»
14 years 11 months ago
Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logari
Background: Classifying nuclear magnetic resonance (NMR) spectra is a crucial step in many metabolomics experiments. Since several multivariate classification techniques depend up...
Helen M. Parsons, Christian Ludwig, Ulrich L. G&uu...
BMCBI
2007
99views more  BMCBI 2007»
14 years 11 months ago
Stratification bias in low signal microarray studies
Background: When analysing microarray and other small sample size biological datasets, care is needed to avoid various biases. We analyse a form of bias, stratification bias, that...
Brian J. Parker, Simon Günter, Justin Bedo
BMCBI
2008
123views more  BMCBI 2008»
14 years 11 months ago
Statistical methodology for the analysis of dye-switch microarray experiments
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
Tristan Mary-Huard, Julie Aubert, Nadera Mansouri-...