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WSC
2000
15 years 6 months ago
A comparison of five steady-state truncation heuristics for simulation
We compare the performance of five well-known truncation heuristics for mitigating the effects of initialization bias in the output analysis of steady-state simulations. Two of th...
K. Preston White, Michael J. Cobb, Stephen C. Spra...
BMCBI
2010
136views more  BMCBI 2010»
15 years 5 months ago
Bias correction and Bayesian analysis of aggregate counts in SAGE libraries
Background: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation proces...
Russell L. Zaretzki, Michael A. Gilchrist, William...
BMCBI
2006
147views more  BMCBI 2006»
15 years 5 months ago
A case study in pathway knowledgebase verification
Background: Biological databases and pathway knowledgebases are proliferating rapidly. We are developing software tools for computer-aided hypothesis design and evaluation, and we...
Stephen A. Racunas, Nigam Shah, Nina V. Fedoroff
BMCBI
2006
127views more  BMCBI 2006»
15 years 5 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2007
105views more  BMCBI 2007»
15 years 5 months ago
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
Background: Vaccine development in the post-genomic era often begins with the in silico screening of genome information, with the most probable protective antigens being predicted...
Irini A. Doytchinova, Darren R. Flower