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BMCBI
2010
87views more  BMCBI 2010»
15 years 3 months ago
poolMC: Smart pooling of mRNA samples in microarray experiments
Background: Typically, pooling of mRNA samples in microarray experiments implies mixing mRNA from several biological-replicate samples before hybridization onto a microarray chip....
Raghunandan M. Kainkaryam, Angela Bruex, Anna C. G...
BMCBI
2010
120views more  BMCBI 2010»
15 years 3 months ago
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
Aarti Garg, Rupinder Tewari, Gajendra P. S. Raghav...
BIOSYSTEMS
2008
129views more  BIOSYSTEMS 2008»
15 years 3 months ago
Reconstruction of DNA sequences using genetic algorithms and cellular automata: Towards mutation prediction?
Change of DNA sequence that fuels evolution is, to a certain extent, a deterministic process because mutagenesis does not occur in an absolutely random manner. So far, it has not ...
Ch. Mizas, Georgios Ch. Sirakoulis, Vasilios A. Ma...
BMCBI
2008
160views more  BMCBI 2008»
15 years 3 months ago
A method for analyzing censored survival phenotype with gene expression data
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
Tongtong Wu, Wei Sun, Shinsheng Yuan, Chun-Houh Ch...
BMCBI
2007
106views more  BMCBI 2007»
15 years 3 months ago
Improved classification accuracy in 1- and 2-dimensional NMR metabolomics data using the variance stabilising generalised logari
Background: Classifying nuclear magnetic resonance (NMR) spectra is a crucial step in many metabolomics experiments. Since several multivariate classification techniques depend up...
Helen M. Parsons, Christian Ludwig, Ulrich L. G&uu...