The Valued Constraint Satisfaction Problem (VCSP) is a generic optimization problem defined by a network of local cost functions defined over discrete variables. It has applicatio...
Martin C. Cooper, Simon de Givry, M. Sanchez, Thom...
Background: High-throughput methods for detecting protein-protein interactions enable us to obtain large interaction networks, and also allow us to computationally identify the as...
Background: Optimization theory has been applied to complex biological systems to interrogate network properties and develop and refine metabolic engineering strategies. For examp...
Erwin P. Gianchandani, Matthew A. Oberhardt, Antho...
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Since the physical topology of Mobile Ad hoc Networks (MANETs) is generally unstable, an appealing approach is the construction of a stable and robust virtual topology or backbone...