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BMCBI
2008
14 years 11 months ago
2008
Background: Microarray gene expression data are often analyzed together with corresponding physiological response and clinical metadata of biological subjects, e.g. patients'...
110
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BMCBI
2008
14 years 11 months ago
2008
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...
146
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BMCBI
2008
14 years 11 months ago
2008
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
BMCBI
2008
14 years 11 months ago
2008
Background: Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing awareness about the importance of pred...
102
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BMCBI
2008
14 years 11 months ago
2008
Background: The models developed to characterize the evolution of multigene families (such as the birth-and-death and the concerted models) have also been applied on the level of ...