This paper presents a requirements engineering framework based on the notions of Actor, Goal, and Intentional Dependency, and applies it to a case study in the field of Informatio...
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...
Paolo G. V. Martini, Davide Risso, Gabriele Sales,...
The deluge of huge data sets such as those provided by
sensor networks, online transactions, and the web provide
exciting opportunities for data analysis. The scale of the
data ...
The increasing amount of genomic and molecular information is the basis for understanding higherorder biological systems, such as the cell and the 15 organism, and their interacti...