Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Background: Recent years have seen the development of various pathway-based methods for the analysis of microarray gene expression data. These approaches have the potential to bri...
Background: Increasing amounts of data from large scale whole genome analysis efforts demands convenient tools for manipulation, visualization and investigation. Whole genome plot...
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
Background: Phylogenies capture the evolutionary ancestry linking extant species. Correlations and similarities among a set of species are mediated by and need to be understood in...