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BMCBI
2010
119views more  BMCBI 2010»
14 years 10 months ago
A comparison of internal validation techniques for multifactor dimensionality reduction
Background: It is hypothesized that common, complex diseases may be due to complex interactions between genetic and environmental factors, which are difficult to detect in high-di...
Stacey J. Winham, Andrew J. Slater, Alison A. Mots...
SIAMSC
2008
198views more  SIAMSC 2008»
14 years 9 months ago
Model Reduction for Large-Scale Systems with High-Dimensional Parametric Input Space
A model-constrained adaptive sampling methodology is proposed for reduction of large-scale systems with high-dimensional parametric input spaces. Our model reduction method uses a ...
T. Bui-Thanh, Karen Willcox, Omar Ghattas
DEXAW
2007
IEEE
157views Database» more  DEXAW 2007»
15 years 1 months ago
Dimensionality Reduction in a P2P System
Peers and data objects in the Hybrid Overlay Network (HON) are organized in a ndimensional feature space. As the dimensionality increases, peers and data objects become sparse and ...
Mouna Kacimi, Kokou Yétongnon
SPEECH
1998
118views more  SPEECH 1998»
14 years 9 months ago
Dimensionality reduction of electropalatographic data using latent variable models
We consider the problem of obtaining a reduced dimension representation of electropalatographic (EPG) data. An unsupervised learning approach based on latent variable modelling is...
Miguel Á. Carreira-Perpiñán, ...
BMCBI
2011
14 years 1 months ago
A Beta-Mixture Model for Dimensionality Reduction, Sample Classification and Analysis
Background: Patterns of genome-wide methylation vary between tissue types. For example, cancer tissue shows markedly different patterns from those of normal tissue. In this paper ...
Kirsti Laurila, Bodil Oster, Claus L. Andersen, Ph...