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BMCBI
2007
14 years 9 months ago
2007
Background: In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the se...
102
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IPPS
2006
IEEE
15 years 3 months ago
2006
IEEE
In this paper we describe a new approach for the well known problem in bioinformatics: Multiple Sequence Alignment (MSA). MSA is fundamental task as it represents an essential pla...
108
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BMCBI
2004
14 years 9 months ago
2004
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
ALMOB
2008
14 years 9 months ago
2008
Motivation: Sequence-based methods for phylogenetic reconstruction from (nucleic acid) sequence data are notoriously plagued by two effects: homoplasies and alignment errors. Larg...
BIBE
2006
IEEE
15 years 3 months ago
2006
IEEE
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...