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BMCBI
2006
14 years 9 months ago
2006
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
BMCBI
2006
2006
A jumping profile Hidden Markov Model and applications to recombination sites in HIV and HCV genomes
14 years 9 months ago
Background: Jumping alignments have recently been proposed as a strategy to search a given multiple sequence alignment A against a database. Instead of comparing a database sequen...
BMCBI
2010
14 years 9 months ago
2010
Background: An algorithm is presented to compute a multiple structure alignment for a set of proteins and to generate a consensus (pseudo) protein which captures common substructu...
BMCBI
2008
14 years 9 months ago
2008
Background: Liquid chromatography coupled to mass spectrometry (LC-MS) has become a prominent tool for the analysis of complex proteomics and metabolomics samples. In many applica...
BMCBI
2006
14 years 9 months ago
2006
Background: In sequence analysis the multiple alignment builds the fundament of all proceeding analyses. Errors in an alignment could strongly influence all succeeding analyses an...