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BMCBI
2010
131views more  BMCBI 2010»
14 years 10 months ago
FACT: Functional annotation transfer between proteins with similar feature architectures
Background: The increasing number of sequenced genomes provides the basis for exploring the genetic and functional diversity within the tree of life. Only a tiny fraction of the e...
Tina Koestler, Arndt von Haeseler, Ingo Ebersberge...
BMCBI
2005
106views more  BMCBI 2005»
14 years 9 months ago
A multistep bioinformatic approach detects putative regulatory elements in gene promoters
Background: Searching for approximate patterns in large promoter sequences frequently produces an exceedingly high numbers of results. Our aim was to exploit biological knowledge ...
Stefania Bortoluzzi, Alessandro Coppe, Andrea Biso...
BMCBI
2004
83views more  BMCBI 2004»
14 years 9 months ago
VKCDB: Voltage-gated potassium channel database
Background: The family of voltage-gated potassium channels comprises a functionally diverse group of membrane proteins. They help maintain and regulate the potassium ion-based com...
Bin Li, Warren J. Gallin
JCB
2002
116views more  JCB 2002»
14 years 9 months ago
A Novel Approach to Remote Homology Detection: Jumping Alignments
We describe a new algorithm for protein classi cation and the detection of remote homologs. The rationale is to exploit both vertical and horizontal information of a multiple alig...
Rainer Spang, Marc Rehmsmeier, Jens Stoye
TJS
2002
160views more  TJS 2002»
14 years 9 months ago
Adaptive Optimizing Compilers for the 21st Century
Historically, compilers have operated by applying a fixed set of optimizations in a predetermined order. We call such an ordered list of optimizations a compilation sequence. This...
Keith D. Cooper, Devika Subramanian, Linda Torczon