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BIOINFORMATICS
2008
119views more  BIOINFORMATICS 2008»
14 years 9 months ago
Optimal design of thermally stable proteins
Motivation: For many biotechnological purposes, it is desirable to redesign proteins to be more structurally and functionally stable at higher temperatures. For example, chemical ...
Ryan M. Bannen, Vanitha Suresh, George N. Phillips...
BMCBI
2008
93views more  BMCBI 2008»
14 years 9 months ago
Homology modelling of protein-protein complexes: a simple method and its possibilities and limitations
Background: Structure-based computational methods are needed to help identify and characterize protein-protein complexes and their function. For individual proteins, the most succ...
Guillaume Launay, Thomas Simonson
NAR
2010
129views more  NAR 2010»
14 years 4 months ago
PROSESS: a protein structure evaluation suite and server
PROSESS (PROtein Structure Evaluation Suite and Server) is a web server designed to evaluate and validate protein structures generated by X-ray crystallography, NMR spectroscopy o...
Mark V. Berjanskii, Yongjie Liang, Jianjun Zhou, P...
KDD
2008
ACM
183views Data Mining» more  KDD 2008»
15 years 10 months ago
Knowledge transfer via multiple model local structure mapping
The effectiveness of knowledge transfer using classification algorithms depends on the difference between the distribution that generates the training examples and the one from wh...
Jing Gao, Wei Fan, Jing Jiang, Jiawei Han
BMCBI
2011
14 years 1 months ago
RegNetB: Predicting Relevant Regulator-Gene Relationships in Localized Prostate Tumor Samples
Background: A central question in cancer biology is what changes cause a healthy cell to form a tumor. Gene expression data could provide insight into this question, but it is dif...
Angel Alvarez, Peter J. Woolf