Sciweavers

36 search results - page 2 / 8
» Local sequence alignments with monotonic gap penalties
Sort
View
BMCBI
2006
139views more  BMCBI 2006»
13 years 6 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
BMCBI
2004
177views more  BMCBI 2004»
13 years 6 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
WABI
2007
Springer
123views Bioinformatics» more  WABI 2007»
14 years 10 days ago
Inverse Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of parameter values for the alignment scoring function is critical. Small changes in gap penalties, for example, can yield radically ...
Eagu Kim, John D. Kececioglu
ISMB
1998
13 years 7 months ago
A Statistical Theory of Sequence Alignment with Gaps
Astatistical theory of local alignmentalgorithms with gaps is presented. Both the linear and logarithmic phases, as well as the phase transition separating the two phases, are des...
Dirk Drasdo, Terence Hwa, Michael Lässig
BMCBI
2007
142views more  BMCBI 2007»
13 years 6 months ago
Predicting and improving the protein sequence alignment quality by support vector regression
Background: For successful protein structure prediction by comparative modeling, in addition to identifying a good template protein with known structure, obtaining an accurate seq...
Minho Lee, Chan-seok Jeong, Dongsup Kim